Buffalo Bills Schedule 2025: Full Preseason and Regular Season Guide
Every new NFL season brings with it anticipation, speculation, and excitement. Fans begin asking: When do the games start? Who are the opponents? Which matchups will shape the season? For the Buffalo Bills, the 2025 season is already off to a promising start.
The team opened its campaign in dramatic fashion, edging the Baltimore Ravens in a thrilling 41-40 victory at Highmark Stadium on September 7.
This high-scoring showdown was not only a strong start but also a statement that Buffalo remains a contender in the AFC. Following that, a decisive 30-10 road win over the New York Jets and a 31-21 triumph against the Miami Dolphins kept momentum rolling into Week 3.
The Buffalo Bills schedule 2025 combines tough divisional clashes, marquee national matchups, community-driven theme games, and the ever-critical playoff push.
Understanding how the schedule is structured provides insight into the challenges and opportunities Buffalo faces in its pursuit of a Super Bowl berth.
How Did the Buffalo Bills Perform in the Preseason?
Preseason often sets the tone for what lies ahead. While the games do not count toward standings, they provide valuable opportunities for rookies and depth players to prove themselves.
The Bills’ preseason 2025 included three matchups:
| Week | Date | Opponent | Location | Result | Notes |
| 1 | Aug 9 | New York Giants | Highmark Stadium | L 25-34 | Kids Day |
| 2 | Aug 17 | Chicago Bears | Soldier Field | L 0-38 | Road setback |
| 3 | Aug 23 | Tampa Bay Buccaneers | Raymond James | W 23-19 | Road win |
The opener, branded as Kids Day Presented by Fisher-Price, gave fans an entertaining shootout despite the loss. Week 2 against the Bears was more sobering, as Buffalo’s offense struggled in a lopsided defeat. However, confidence returned in Week 3 with a narrow win over the Buccaneers.
Preseason outcomes rarely predict regular-season performance, but Buffalo’s ability to recover in Week 3 showed resilience in its depth players.
Which Games Defined the Bills’ Strong Start in September?
The regular season began with fireworks. Buffalo immediately put the league on notice in Week 1 by outlasting the Ravens at home in a one-point thriller. The Kickoff Game was emblematic of Buffalo’s offensive firepower, led by quarterback Josh Allen.
In Week 2, the Bills traveled to MetLife Stadium and dismantled the New York Jets. A 30-10 win emphasized balance on both sides of the ball, as the defense contained New York’s attack while the offense dictated the game.
Week 3 saw the Bills return home to Orchard Park for a divisional clash against the Miami Dolphins. This matchup carried added significance as it coincided with Hispanic Heritage and Bills HEARTBEAT Night.
The Bills prevailed 31-21, strengthening their grip early in the AFC East standings.
These victories provided Buffalo with an enviable 3 – 0 start, sparking optimism across Western New York and beyond.
Who Are the Buffalo Bills’ Home Opponents in 2025?
Highmark Stadium remains one of the toughest venues for visiting teams, and in 2025, it is hosting a variety of high-profile contests.
- Week 1: Ravens – A season opener remembered for its offensive fireworks.
- Week 3: Dolphins – Divisional clash and cultural celebration.
- Week 4: Saints – A matchup aligned with the NFL’s Crucial Catch campaign, promoting cancer awareness.
- Week 5: Patriots –The storied rivalry took center stage on Sunday Night Football under the theme Huddle for Hunger.
- Week 9: Chiefs – A rematch of frequent AFC playoff battles, scheduled during Salute to Service week.
- Week 11: Buccaneers – Recognizing Native American Heritage.
- Week 14: Bengals – A showcase that honored the Walter Payton NFL Man of the Year and Coach of the Week initiatives.
- Week 17: Eagles – A cross-conference clash tied to Play 60 and Inspire Change.
- Week 18: Jets – A divisional finale branded as a Farewell Celebration and Red Helmet Game.
Each of these games not only contributes to Buffalo’s win-loss record but also weaves in community themes that enhance the fan experience.
Which Away Games Will Test the Bills Most in 2025?
The road always presents challenges, and Buffalo faces several pivotal contests away from Orchard Park.
In Week 6, the Bills meet the Atlanta Falcons in Mercedes-Benz Stadium on Monday Night Football. This nationally televised contest will test Buffalo’s composure under bright lights and against a rising NFC South team.
Two weeks later, Week 8 features a trip to Charlotte, where Buffalo will take on the Carolina Panthers. Road trips to NFC opponents are always unpredictable, particularly in hostile environments.
Perhaps the most significant away game comes in Week 12, when Buffalo travels to Houston for a Thursday Night Football clash against the Texans. With playoff implications likely, this game’s prime-time slot elevates its importance.
Other notable road challenges include divisional trips to Miami and New England, along with late-season cold-weather battles against the Steelers in Week 13 and the Browns in Week 16. Success in these contests could determine playoff seeding.
When Is the Buffalo Bills’ Bye Week?
The Bills enjoy their bye in Week 7, which falls in mid-October. A midseason bye is often ideal, giving the team time to recover from injuries sustained early while preparing for the second half of the season.
This placement allows coaches to make necessary adjustments before a grueling stretch that includes the Chiefs, Dolphins, and Texans.
How Many Primetime Games Do the Bills Have in 2025?
Buffalo continues to command national attention, with several games under the prime-time spotlight.
- Week 5 vs Patriots – Sunday Night Football on NBC.
- Week 6 at Falcons – Monday Night Football on ESPN.
- Week 12 at Texans – Thursday Night Football on Prime Video.
These contests are not just showcases of Buffalo’s talent but also opportunities to strengthen its brand on the national stage. Success in these moments helps define the team’s reputation as a perennial contender.
What Are the Special Theme Games in 2025?
The Buffalo Bills are not only competing on the field but also making statements through themed games that highlight causes, celebrate culture, and give back to the community.
Examples include:
- Crucial Catch vs the Saints – Raising awareness for cancer prevention and research.
- Huddle for Hunger vs Patriots – A rivalry matchup with a charitable mission.
- Salute to Service vs Chiefs – Honoring military personnel and veterans.
- Inspire Change vs Eagles – A late-season initiative supporting community empowerment.
By incorporating these themes, the Bills create a deeper bond with fans while aligning the franchise with meaningful campaigns.
What Does the Full Buffalo Bills 2025 Schedule Look Like?
Here is the complete view of Buffalo’s 2025 journey:
| Week | Date | Opponent | Location | Time (ET) | Result | Notes |
|---|---|---|---|---|---|---|
| Pre 1 | Aug 9 | New York Giants | Highmark Stadium | Final | L 25-34 | Kids Day |
| Pre 2 | Aug 17 | Chicago Bears | Soldier Field | Final | L 0-38 | – |
| Pre 3 | Aug 23 | Tampa Bay Buccaneers | Raymond James | Final | W 23-19 | – |
| 1 | Sep 7 | Baltimore Ravens | Highmark Stadium | Final | W 41-40 | Kickoff |
| 2 | Sep 14 | New York Jets | MetLife Stadium | Final | W 30-10 | Road win |
| 3 | Sep 18 | Miami Dolphins | Highmark Stadium | Final | W 31-21 | Heritage Game |
| 4 | Sep 28 | New Orleans Saints | Highmark Stadium | 1:00 PM | – | Crucial Catch |
| 5 | Oct 5 | New England Patriots | Highmark Stadium | 8:20 PM | – | Rivalry Game |
| 6 | Oct 13 | Atlanta Falcons | Mercedes-Benz Dome | 7:15 PM | – | MNF |
| 7 | Oct 19 | Bye Week | – | – | – | – |
| 8 | Oct 26 | Carolina Panthers | Bank of America | 1:00 PM | – | – |
| 9 | Nov 2 | Kansas City Chiefs | Highmark Stadium | 4:25 PM | – | Salute to Service |
| 10 | Nov 9 | Miami Dolphins | Hard Rock Stadium | 1:00 PM | – | Divisional Game |
| 11 | Nov 16 | Tampa Bay Buccaneers | Highmark Stadium | 1:00 PM | – | Heritage |
| 12 | Nov 20 | Houston Texans | NRG Stadium | 8:15 PM | – | TNF |
| 13 | Nov 30 | Pittsburgh Steelers | Acrisure Stadium | 4:25 PM | – | Road Test |
| 14 | Dec 7 | Cincinnati Bengals | Highmark Stadium | 4:25 PM | – | Walter Payton Award |
| 15 | Dec 14 | New England Patriots | Gillette Stadium | 1:00 PM | – | Divisional Game |
| 16 | Dec 21 | Cleveland Browns | Huntington Bank | 1:00 PM | – | – |
| 17 | Dec 28 | Philadelphia Eagles | Highmark Stadium | 4:25 PM | – | Inspire Change |
| 18 | TBD | New York Jets | Highmark Stadium | TBD | – | Farewell Celebration |
What Are the Buffalo Bills’ Playoff Chances in 2025?
With an early 3-0 start and a roster anchored by stars like Josh Allen and Stefon Diggs, Buffalo is in position to make another postseason run. The schedule, however, is far from easy. Games against Kansas City, Cincinnati, and Philadelphia will serve as benchmarks.
Divisional play will be crucial, particularly against the Miami Dolphins, who continue to improve, and the Patriots, who always elevate their intensity against Buffalo. The Bills’ ability to capitalize on home-field advantage while stealing key wins on the road will dictate their seeding.
If Buffalo maintains its current trajectory, another playoff appearance looks not only possible but likely.
FAQs – Buffalo Bills 2025 Schedule
How many home games do the Bills play in 2025?
Buffalo will host nine home games at Highmark Stadium under the 17-game NFL format.
What was Buffalo’s preseason record?
They finished 1–2, winning against the Buccaneers but losing to the Giants and Bears.
When is the Bills’ bye week?
The bye week falls in Week 7, offering a midseason break.
Which primetime games feature the Bills?
Buffalo has Sunday Night Football in Week 5, Monday Night Football in Week 6, and Thursday Night Football in Week 12.
What is the theme for the Week 9 game against the Chiefs?
That game is part of the NFL’s Salute to Service initiative.
Which game might be the most difficult?
Analysts view Week 9 against Kansas City and Week 14 against Cincinnati as the toughest matchups.
Will Buffalo wear alternate helmets in 2025?
Yes, the team will wear red helmets during the Week 18 Farewell Celebration Game against the Jets.
